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Why Get Tested?
To evaluate the health of your kidneys; to help diagnose kidney disease; to monitor treatment for kidney disease
When To Get Tested?
Routinely as part of a comprehensive or basic metabolic panel; when your have signs and symptoms that may be due to kidney disease or damage or when you have a condition that may affect your kidneys and/or be worsened by kidney dysfunction; at intervals to monitor treatment for kidney disease or kidney function while on certain medications
Sample Type:
SERUM (SST or Plain)
Fasting :
NO
Report Delivery:
Same day (if Collected before 12 Noon)
Components:
1 Observations

Tests Detail

Observations Included

Creatinine

The Test marked with (*) are in our NABL Scope.

Sample Report

Test Name	Creatinine
Report Availability	Same day (if Collected before 12 Noon)
Code	C1079
Category	SR-Special Routine
Schedule	Daily
TAT*	0
Tested At*	NPL
Method	Jaffes
Brief Description	To diagnose & monitor renal function.

*Reporting TAT in days
for the samples recieved by 4PM

*0 = Same Day, 1 = Next Day, 2 = 2nd Day,
3 = 3rd Day So on from Schedule

*NPL : Tested @ nirAmaya Pathlabs
NRL : Tested @ NPL Outsource lab

Also Known As:
Creat Blood Creatinine Serum Creatinine Urine Creatinine
Formal Name:
Creatinine
Sample Instructions:
A blood sample drawn from a vein in your arm and/or a 24-hour urine sample
Test Preparation Needed?
You may be instructed to fast overnight or refrain from eating cooked meat; some studies have shown that eating cooked meat prior to testing can temporarily increase the level of creatinine.
What Is Being Tested?
Creatinine is a waste product produced by muscles from the breakdown of a compound called creatine. Creatinine is removed from the body by the kidneys, which filter almost all of it from the blood and release it into the urine. This test measures the amount of creatinine in the blood and/or urine. Creatine is part of the cycle that produces energy needed to contract muscles. Both creatine and creatinine are produced by the body at a relatively constant rate. Since almost all creatinine is filtered from the blood by the kidneys and released into the urine, blood levels are usually a good indicator of how well the kidneys are working. The quantity produced depends on the size of the person and their muscle mass. For this reason, creatinine concentrations will be slightly higher in men than in women and children. Results from a blood creatinine test may be used in combination with results from other tests, such as a 24-hour urine creatinine test, to perform calculations that are used to evaluate kidney function. See the "How is it used?" section under Common Questions. How is the sample collected for testing? A blood sample is drawn from a vein in the arm. A 24-hour urine sample may also be collected, in which all urine produced during 24 hours is saved. Sometimes a single, random urine sample may be collected and tested. Is any test preparation needed to ensure the quality of the sample? You may be instructed to fast overnight or refrain from eating cooked meat; some studies have shown that eating cooked meat prior to testing can temporarily increase the level of creatinine. If a 24-hour urine sample is being collected, it is important to save all of the urine produced during that time period.
How Is It Used?
The creatinine blood test is used to assess kidney function. It is frequently ordered along with a BUN (blood urea nitrogen) test or as part of a basic or comprehensive metabolic panel (BMP or CMP), groups of tests that are performed to evaluate the function of the body's major organs. BMP or CMP tests are used to screen healthy people during routine physical exams and to help evaluate acutely or chronically ill people in the emergency room and/or hospital. Sometimes, creatinine may be performed as part of a renal panel to evaluate kidney function. Creatinine is a waste product produced by muscles from the breakdown of a compound called creatine. Almost all creatinine is filtered from the blood by the kidneys and released into the urine, so blood levels are usually a good indicator of how well the kidneys are working. The kidneys are a pair of bean-shaped organs that are located at the bottom of the ribcage in the right and left sides of the back. Within them are about a million tiny blood filtering units called nephrons. In each nephron, blood is continually filtered through a microscopic cluster of looping blood vessels, called a glomerulus. The glomerulus allows the passage of water and small molecules but retains blood cells and larger molecules. Attached to each glomerulus is a tiny tube (tubule) that collects the fluid and molecules that pass through the glomerulus and then reabsorbs what can be used by the body. The remaining waste forms urine. If the creatinine and BUN tests are found to be abnormal or if someone has an underlying disease that is known to affect the kidneys, such as diabetes or high blood pressure, then creatinine and BUN tests may be used to monitor for kidney dysfunction and the effectiveness of treatment. Blood creatinine and BUN tests may also be ordered to evaluate kidney function prior to some procedures, such as a CT (computed tomography) scan, that may require the use of drugs that can damage the kidneys. Results from creatinine
When Is It Ordered
Creatinine may be ordered routinely as part of a comprehensive or basic metabolic panel during a health examination. It may be ordered when someone is acutely ill and/or when a health practitioner suspects that a person's kidneys are not working properly. Some signs and symptoms of kidney dysfunction include: Fatigue, lack of concentration, poor appetite, or trouble sleeping Swelling or puffiness, particularly around the eyes or in the face, wrists, abdomen, thighs or ankles Urine that is foamy, bloody, or coffee-colored A decrease in the amount of urine Problems urinating, such as a burning feeling or abnormal discharge during urination, or a change in the frequency of urination, especially at night Mid-back pain (flank), below the ribs, near where the kidneys are located High blood pressure The creatinine blood test may be ordered, along with a BUN test and urine albumin, at regular intervals when someone has a known kidney disorder or has a disease that may affect kidney function. Both BUN and creatinine may be ordered when a CT scan is planned, prior to and during certain drug therapies, and before and after dialysis to monitor the effectiveness of treatments.
What Does The Test Result Mean?
Increased creatinine levels in the blood suggest kidney disease or other conditions that affect kidney function. These can include: Damage to or swelling of blood vessels in the kidneys (glomerulonephritis) caused by, for example, infection or autoimmune diseases Bacterial infection of the kidneys (pyelonephritis) Death of cells in the kidneys' small tubes (acute tubular necrosis) caused by, for example, drugs or toxins Prostate disease, kidney stone, or other causes of urinary tract obstruction Reduced blood flow to the kidney due to shock, dehydration, congestive heart failure, atherosclerosis, or complications of diabetes Low blood levels of creatinine are not common, but they are also not usually a cause for concern. They can be seen with conditions that result in decreased muscle mass. Levels of 24-hour urine creatinine are evaluated with blood levels as part of a creatinine clearance test. Single, random urine creatinine levels have no standard reference ranges. They are usually used with other tests to reference levels of other substances measured in the urine. Some examples include the urine albumin test and urine albumin/creatinine ratio and the urine protein test.
Is There Anything Else I Should Known?
Creatinine blood levels can also increase temporarily as a result of muscle injury and are generally slightly lower during pregnancy. Some drugs may cause increased creatinine levels. Inform your healthcare provider of any drugs you are taking.

Creatinine

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