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Why Get Tested?
Hepatic Function Panel
When To Get Tested?
To screen for, detect, evaluate, and monitor acute and chronic liver inflammation (hepatitis), liver infection, liver disease and/or and damage
Sample Type:
SERUM (SST or Plain)
Fasting :
NO
Report Delivery:
Same day (if Collected before 12 Noon)
Components:
12 Observations

Tests Detail

Observations Included

Bilirubin Indirect *

Albumin / Globulin Ratio (A/G) *

SGOT / SGPT Ratio *

Bilirubin Total *

Bilirubin Direct *

Aspartate Aminotransferase (AST/SGOT) *

Alanine amino Transferase - (ALT / SGPT) *

Alkaline Phosphatase ( ALP ) *

Gamma Glutamyl Transferase (GGT) *

Protein Total *

Albumin *

Globulin *

The Test marked with (*) are in our NABL Scope.

Sample Report

Test Name	Liver Function Test (LFT) - Extended
Report Availability	Same day (if Collected before 12 Noon)
Code	P034
Category	SPL-Special Offers
Schedule	Daily
TAT*	0
Tested At*	NPL
Method	DPD Surfactant,DPD,Calculated,IFCC with pyridoxal phosphate,IFCC with Pyridoxal Phosphate,IFCC/PNPP,IFCC/yGT,Biuret,Bromocresol Green
Brief Description	Alanine amino Transferase - (ALT / SGPT), Albumin, Albumin/Globulin Ratio (A/G), Alkaline Phosphatase (ALP), Aspartate Aminotransferase (AST/SGOT), Bilirubin Direct, Bilirubin Indirect, Bilirubin Total, Gamma Glutamyl Transferase (GGT), Globulin, Protein Total

*Reporting TAT in days
for the samples recieved by 4PM

*0 = Same Day, 1 = Next Day, 2 = 2nd Day,
3 = 3rd Day So on from Schedule

*NPL : Tested @ nirAmaya Pathlabs
NRL : Tested @ NPL Outsource lab

Also Known As:
Liver Panel
Formal Name:
Liver Profile Liver Function Tests LFTs
Sample Instructions:
Periodically to evaluate liver function; whenever you are at risk for liver injury; when you are taking medications that may affect your liver; when you have a liver disease; when you have symptoms associated with liver damage, such as jaundice
Test Preparation Needed?
A blood sample drawn from a vein in your arm; for infants, blood may be drawn by puncturing the heel with a lancet.
What Is Being Tested?
You may be instructed to fast overnight with only water permitted. Follow any instructions you are given. Inform the healthcare practitioner about all prescription and over-the-counter medications, herbal medications, vitamins and supplements you are taking.
How Is It Used?
A liver panel is a group of tests that are performed together to detect, evaluate, and monitor liver disease or damage. The liver is one of the largest organs in the body and is located in the upper right-hand part of the abdomen and behind the lower ribs. The liver metabolizes and detoxifies drugs and substances that are harmful to the body. It produces blood clotting factors, proteins, and enzymes, helps maintain hormone balances, and stores vitamins and minerals. Bile, a fluid produced by the liver, is transported through ducts directly to the small intestine to help digest fats or to the gallbladder to be stored and concentrated for later use. A variety of diseases and infections can cause acute or chronic damage to the liver, causing inflammation (hepatitis), scarring (cirrhosis), bile duct obstructions, liver tumors, and liver dysfunction. Alcohol, drugs, some herbal supplements, and toxins can also pose a threat. A significant amount of liver damage may be present before symptoms such as jaundice, dark urine, light-colored stools, itching (pruritus), nausea, fatigue, diarrhea, and unexplained weight loss or gain emerge. Early detection is essential in order to minimize damage and preserve liver function. The liver panel measures enzymes, proteins, and substances that are produced, processed or eliminated by the liver and are affected by liver injury. Some are released by damaged liver cells and some reflect a decrease in the liver's ability to perform one or more of its functions. When performed together, these tests give a healthcare practitioner a snapshot of the health of a person's liver, an indication of the potential severity of any liver injury, change in liver status over time, and a starting place for further diagnostic testing.
When Is It Ordered
A liver panel may be used to screen for liver damage, especially if someone has a condition or is taking a drug that may affect the liver. A comprehensive metabolic panel (CMP), which is often performed as part of a general health checkup, may be ordered instead of a liver panel for routine screening. This group of tests includes most of the liver panel as well as additional tests that evaluate other organs and systems within the body. A liver panel or one or more of its component tests may be used to help diagnose liver disease if a person has signs and symptoms that indicate possible liver dysfunction. If a person has a known condition or liver disease, testing may be performed at intervals to monitor the health of the liver and to evaluate the effectiveness of any treatments. A series of bilirubin tests, for instance, may be ordered to evaluate and monitor a jaundiced newborn. Abnormal tests on a liver panel may prompt a repeat analysis of one or more tests, or of the whole panel, to see if the elevations or decreases persist and/or may indicate the need for additional testing to determine the cause of the liver dysfunction. The panel usually consists of several tests that are run at the same time on a blood sample. These typically include: Alanine aminotransferase (ALT) – an enzyme mainly found in the liver; the best test for detecting hepatitis Alkaline phosphatase (ALP) – an enzyme related to the bile ducts but also produced by the bones, intestines, and during pregnancy by the placenta (afterbirth); often increased when bile ducts are blocked. Aspartate aminotransferase (AST) – an enzyme found in the liver and a few other organs, particularly the heart and other muscles in the body Bilirubin – two different tests of bilirubin often used together (especially if a person has jaundice): total bilirubin measures all the bilirubin in the blood; direct bilirubin measures a form that is conjugated (combined with another compound) in the liver.
What Does The Test Result Mean?
A liver panel, or one or more of its components, may be ordered when someone is at risk for liver dysfunction. Some examples include: People who take medications that may potentially damage the liver Those who are alcoholics or heavy drinkers Those who have a history of known or possible exposure to hepatitis viruses Individuals whose families have a history of liver disease People who are overweight, especially if they have diabetes and/or high blood pressure A liver panel may be ordered when a person has signs and symptoms of liver disease; however, most people who have liver disease do not have any of these symptoms until the disease has been present for many years or is very severe. Some of these include: Weakness, fatigue Loss of appetite Nausea, vomiting Abdominal swelling and/or pain Jaundice (yellowing of eyes or skin) Dark urine, light-colored stool Itching (pruritus) Diarrhea Usually no one single set of liver tests is used to make a diagnosis. Often, several liver panels will be ordered over a few days or weeks to help determine the cause of the liver disorder and evaluate its severity. When liver disease is detected, it may be monitored on a regular basis over time with the liver panel or with one or more of its components. A liver panel may also be ordered regularly to monitor the effectiveness of treatment for the liver disorder.
Is There Anything Else I Should Known?
Liver panel test results are not diagnostic of a specific condition; they indicate that there may be a problem with the liver. In a person who does not have symptoms or identifiable risk factors, abnormal liver test results may indicate a temporary liver injury or reflect something that is happening elsewhere in the body – such as in the skeletal muscles, pancreas, or heart. It may also indicate early liver disease and the need for further testing and/or periodic monitoring. Results of liver panels are usually evaluated together. Several sets of results from tests performed over a few days or weeks are often assessed together to determine if a pattern is present. Each person will have a unique set of test results that will typically change over time. A healthcare practitioner evaluates the combination of liver test results to gain clues about the underlying condition. Often, further testing is necessary to determine what is causing the liver damage and/or disease. This table shows examples of some combinations of results that may be seen in certain types of liver conditions or diseases. Type of liver condition or disease Bilirubin ALT and AST ALP Albumin PT Acute liver damage (due, for example, to infection, toxins or drugs, etc.) Normal or increased usually after ALT and AST are already increased Usually greatly increased (> 10 times); ALT is usually higher than AST Normal or only moderately increased Normal Usually normal Chronic forms of various liver disorders Normal or increased Mildly or moderately increased; ALT is persistently increased Normal to slightly increased Normal Normal Alcoholic Hepatitis Normal or increased AST is moderately increased, usually at least twice the level of ALT Normal or moderately increased Normal Normal Cirrhosis May be increased but this usually occurs later in the disease AST is usually higher than ALT but levels are usually lower than in alcoholic disease Normal or increased Normal or decreased Usually

Liver Function Test (LFT) - Extended

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